Research
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Lectins from fungal fruiting bodies face the biologically relevant challenge of discriminating self- from non-self carbohydrate structures, therefore providing the basis for an innate defense system.
Read more: A new β-trefoil at atomic resolution: its role in the fungal innate immune system.
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Certain sequences of our genome can adopt an unusual structure, known as i-DNA, which is able to change its structure to adapt to the environmental pH.
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Cyclosporin (CsA) has antiparasite activity against the human pathogen Toxoplasma gondii. We characterized the functional and structural properties of two cyclophilins from T. gondii, TgCyp23 and TgCyp18.4.
Read more: Search for new drugs against toxoplasmosis. Interaction study for cyclophilin inhibition.
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Aberrant TDP-43 phase transitions, which are primed by oxidative stress and chaperone inhibition, command molecular malfunction in several neurodegenerative diseases.
Read more: Understanding the impact of post-translational modifications in TDP-43 pathophysiology
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This study reveals that trace atmospheric gases thought to be pollutants are also produced by marine plankton and emitted by the ocean, with potential climate effects.
Read more: Emissions of unexpected gases from marine life affect the air over the poles
